Irotin (Isotretinoin) is used to treat severe recalcitrant nodular acne (a certain type of severe acne) that has not been helped by other treatments, such as antibiotics. Isotretinoin is in a class of medications called retinoids. It works by slowing the production of certain natural substances that can cause pimples to form.

How should this medication be used?
Isotretinoin comes as a capsule to take by mouth. Isotretinoin is usually taken twice a day with meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isotretinoin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the capsules whole with a full glass of liquid. Do not chew or suck on the capsules.
It may take several weeks or longer for you to feel the full benefit of isotretinoin. Your acne may get worse during the beginning of your treatment with isotretinoin. This is normal and does not mean that the medication is not working.

Other uses for Isotretinoin
This medicine has been used to treat certain other skin conditions and some types of cancer. This medication may be prescribed for other uses. Ask your healthcare professional for more information.

What side effects can Isotretinoin cause?
This medication may cause side effects: red, cracked, and sore lips; dry skin, eyes, mouth, or nose; nosebleeds; changes in skin color; peeling skin, especially on the palms and soles; changes in the nails; slowed healing of cuts or sores; bleeding or swollen gums; hair loss or unwanted hair growth; sweating; flushing; voice changes; tiredness; cold symptoms; headache; blurred vision; dizziness; nausea; vomiting; seizures; slow or difficult speech; weakness or numbness of one part or side of the body; stomach pain; chest pain; difficulty swallowing or pain when swallowing; new or worsening heartburn; diarrhea; rectal bleeding; yellowing of the skin or eyes; dark colored urine; back, bone, joint or muscle pain; muscle weakness.